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Merck and Pfizer Reports Results of Avelumab in P-III JAVELIN Ovarian 100 study for Previously Untreated Advanced Ovarian Cancer

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Merck and Pfizer Reports Results of Avelumab in P-III JAVELIN Ovarian 100 study for Previously Untreated Advanced Ovarian Cancer

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  • The P-III JAVELIN Ovarian 100 study involves assessing of avelumab + and/or following Pt-based carboplatin/paclitaxel CT in 998 patients with LA or metastatic (Stage III or Stage IV) epithelial ovarian cancer- fallopian tube cancer (FTC)- or primary peritoneal cancer
  • The study resulted in unmet 1EPs as PFS and has shown no new safety signals with consistent safety profile
  • Avelumab is anti-programmed death ligand-1 (PD-L1) Ab that blocks its interaction with PD-L1 with PD-1 receptors. In- 2014 Merck and Pfizer collaborates to co-develop and co-commercialize avelumab

Ref: Pfizer | Image: Buzzercast


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